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Depolarization and Hyperexcitability of Cortical Motor Neurons after Spinal Cord Injury Associates with Reduced HCN Channel Activity

A spinal cord injury (SCI) damages the axonal projections of neurons residing in the neocortex. This axotomy changes cortical excitability and results in dysfunctional activity and output of infragranular cortical layers. Thus, addressing cortical pathophysiology after SCI will be instrumental in pr...

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Detalles Bibliográficos
Autores principales: Benedetti, Bruno, Bieler, Lara, Erhardt-Kreutzer, Christina, Jakubecova, Dominika, Benedetti, Ariane, Reisinger, Maximilian, Dannehl, Dominik, Thome, Christian, Engelhardt, Maren, Couillard-Despres, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003573/
https://www.ncbi.nlm.nih.gov/pubmed/36902146
http://dx.doi.org/10.3390/ijms24054715