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Loss of Blood-Brain Barrier Integrity in an In Vitro Model Subjected to Intermittent Hypoxia: Is Reversion Possible with a HIF-1α Pathway Inhibitor?

Several sleep-related breathing disorders provoke repeated hypoxia stresses, which potentially lead to neurological diseases, such as cognitive impairment. Nevertheless, consequences of repeated intermittent hypoxia on the blood-brain barrier (BBB) are less recognized. This study compared two method...

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Detalles Bibliográficos
Autores principales: Voirin, Anne Cloé, Chatard, Morgane, Briançon-Marjollet, Anne, Pepin, Jean Louis, Perek, Nathalie, Roche, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003655/
https://www.ncbi.nlm.nih.gov/pubmed/36902491
http://dx.doi.org/10.3390/ijms24055062