MUC1 Expression Affects the Immunoflogosis in Renal Cell Carcinoma Microenvironment through Complement System Activation and Immune Infiltrate Modulation

Mucin1 (MUC1), a glycoprotein associated with an aggressive cancer phenotype and chemoresistance, is aberrantly overexpressed in a subset of clear cell renal cell carcinoma (ccRCC). Recent studies suggest that MUC1 plays a role in modulating cancer cell metabolism, but its role in regulating immunof...

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Detalles Bibliográficos
Autores principales: Lucarelli, Giuseppe, Netti, Giuseppe Stefano, Rutigliano, Monica, Lasorsa, Francesco, Loizzo, Davide, Milella, Martina, Schirinzi, Annalisa, Fontana, Antonietta, Di Serio, Francesca, Tamma, Roberto, Ribatti, Domenico, Battaglia, Michele, Ranieri, Elena, Ditonno, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003656/
https://www.ncbi.nlm.nih.gov/pubmed/36902242
http://dx.doi.org/10.3390/ijms24054814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003656/
https://www.ncbi.nlm.nih.gov/pubmed/36902242
http://dx.doi.org/10.3390/ijms24054814

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