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Synthetic Glabridin Derivatives Inhibit LPS-Induced Inflammation via MAPKs and NF-κB Pathways in RAW264.7 Macrophages

Glabridin is a polyphenolic compound with reported anti-inflammatory and anti-oxidative effects. In the previous study, we synthesized glabridin derivatives—HSG4112, (S)-HSG4112, and HGR4113—based on the structure–activity relationship study of glabridin to improve its biological efficacy and chemic...

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Detalles Bibliográficos
Autores principales: Shin, Jaejin, Choi, Leo Sungwong, Jeon, Hyun Ju, Lee, Hyeong Min, Kim, Sang Hyo, Kim, Kwan-Woo, Ko, Wonmin, Oh, Hyuncheol, Park, Hyung Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004008/
https://www.ncbi.nlm.nih.gov/pubmed/36903379
http://dx.doi.org/10.3390/molecules28052135