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Synthetic Glabridin Derivatives Inhibit LPS-Induced Inflammation via MAPKs and NF-κB Pathways in RAW264.7 Macrophages
Glabridin is a polyphenolic compound with reported anti-inflammatory and anti-oxidative effects. In the previous study, we synthesized glabridin derivatives—HSG4112, (S)-HSG4112, and HGR4113—based on the structure–activity relationship study of glabridin to improve its biological efficacy and chemic...
Autores principales: | Shin, Jaejin, Choi, Leo Sungwong, Jeon, Hyun Ju, Lee, Hyeong Min, Kim, Sang Hyo, Kim, Kwan-Woo, Ko, Wonmin, Oh, Hyuncheol, Park, Hyung Soon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004008/ https://www.ncbi.nlm.nih.gov/pubmed/36903379 http://dx.doi.org/10.3390/molecules28052135 |
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