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Zoledronate/Anti-VEGF Neutralizing Antibody Combination Administration Increases Osteal Macrophages in a Murine Model of MRONJ Stage 0-like Lesions

The pathophysiology, pathogenesis, histopathology, and immunopathology of medication-related osteonecrosis of the jaw (MRONJ) Stage 0 remain unclear, although 50% of MRONJ Stage 0 cases could progress to higher stages. The aim of this study was to investigate the effects of zoledronate (Zol) and ant...

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Detalles Bibliográficos
Autores principales: Kaneko, Haruka, Kuroshima, Shinichiro, Kozutsumi, Ryohei, Al-Omari, Farah A., Hayano, Hiroki, Nakajima, Kazunori, Sawase, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004236/
https://www.ncbi.nlm.nih.gov/pubmed/36902701
http://dx.doi.org/10.3390/jcm12051914