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Case report: ATIC-ALK fusion in infant-type hemispheric glioma and response to lorlatinib

INTRODUCTION: Infant type hemispheric gliomas are a rare tumor with unique molecular characteristics. In many cases these harbor mutations in receptor tyrosine kinase pathways and respond to targeted therapy. Here we describe the case of an infant with this type of tumor with a novel ATIC-ALK fusion...

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Detalles Bibliográficos
Autores principales: Shahab, Shubin W., Schniederjan, Matthew, Vega, Jose Velazquez, Little, Stephen, Reisner, Andrew, MacDonald, Tobey, Aguilera, Dolly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004274/
https://www.ncbi.nlm.nih.gov/pubmed/36910660
http://dx.doi.org/10.3389/fonc.2023.1123378