Identification of MGMT Downregulation Induced by miRNA in Glioblastoma and Possible Effect on Temozolomide Sensitivity

Glioblastoma multiforme (GBM) remains one of the tumors with the worst prognosis. In recent years, a better overall survival (OS) has been described in cases subjected to Gross Total Resection (GTR) that were presenting hypermethylation of Methylguanine-DNA methyltransferase (MGMT) promoter. Recentl...

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Detalles Bibliográficos
Autores principales: Cardia, Andrea, Epistolio, Samantha, Zaed, Ismail, Sahnane, Nora, Cerutti, Roberta, Cipriani, Debora, Barizzi, Jessica, Spina, Paolo, Stefanini, Federico Mattia, Cerati, Michele, Balbi, Sergio, Mazzucchelli, Luca, Sessa, Fausto, Pesce, Gianfranco Angelo, Reinert, Michael, Frattini, Milo, Marchi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004383/
https://www.ncbi.nlm.nih.gov/pubmed/36902848
http://dx.doi.org/10.3390/jcm12052061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004383/
https://www.ncbi.nlm.nih.gov/pubmed/36902848
http://dx.doi.org/10.3390/jcm12052061

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