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General Strategies for RNA X-ray Crystallography

An extremely small proportion of the X-ray crystal structures deposited in the Protein Data Bank are of RNA or RNA–protein complexes. This is due to three main obstacles to the successful determination of RNA structure: (1) low yields of pure, properly folded RNA; (2) difficulty creating crystal con...

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Detalles Bibliográficos
Autores principales: Jackson, Ryland W., Smathers, Claire M., Robart, Aaron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004510/
https://www.ncbi.nlm.nih.gov/pubmed/36903357
http://dx.doi.org/10.3390/molecules28052111