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Shapify: Paths to SARS-CoV-2 frameshifting pseudoknot

Multiple coronaviruses including MERS-CoV causing Middle East Respiratory Syndrome, SARS-CoV causing SARS, and SARS-CoV-2 causing COVID-19, use a mechanism known as −1 programmed ribosomal frameshifting (−1 PRF) to replicate. SARS-CoV-2 possesses a unique RNA pseudoknotted structure that stimulates...

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Detalles Bibliográficos
Autores principales: Trinity, Luke, Wark, Ian, Lansing, Lance, Jabbari, Hosna, Stege, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004594/
https://www.ncbi.nlm.nih.gov/pubmed/36854032
http://dx.doi.org/10.1371/journal.pcbi.1010922