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Shapify: Paths to SARS-CoV-2 frameshifting pseudoknot
Multiple coronaviruses including MERS-CoV causing Middle East Respiratory Syndrome, SARS-CoV causing SARS, and SARS-CoV-2 causing COVID-19, use a mechanism known as −1 programmed ribosomal frameshifting (−1 PRF) to replicate. SARS-CoV-2 possesses a unique RNA pseudoknotted structure that stimulates...
Autores principales: | Trinity, Luke, Wark, Ian, Lansing, Lance, Jabbari, Hosna, Stege, Ulrike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004594/ https://www.ncbi.nlm.nih.gov/pubmed/36854032 http://dx.doi.org/10.1371/journal.pcbi.1010922 |
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