2-Amino-1,3-benzothiazole: Endo N-Alkylation with α-Iodo Methyl Ketones Followed by Cyclization

Reactions of 2-amino-1,3-benzothiazole with aliphatic, aromatic and heteroaromatic α-iodoketones in the absence of bases or catalysts have been studied. The reaction proceeds by N-alkylation of the endocyclic nitrogen atom followed by intramolecular dehydrative cyclization. The regioselectivity is e...

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Detalles Bibliográficos
Autores principales: Dorofeev, Ivan A., Zhilitskaya, Larisa V., Yarosh, Nina O., Shainyan, Bagrat A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004639/
https://www.ncbi.nlm.nih.gov/pubmed/36903340
http://dx.doi.org/10.3390/molecules28052093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004639/
https://www.ncbi.nlm.nih.gov/pubmed/36903340
http://dx.doi.org/10.3390/molecules28052093

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