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Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides

Sortase A (SrtA) is an enzyme which attaches proteins, including virulence factors, to bacterial cell walls. It is a potential target for developing anti-virulence agents against pathogenic and antimicrobial resistant bacteria. This study aimed to engineer 𝛽-lactoglobulin protein nanoparticles (PNPs...

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Detalles Bibliográficos
Autores principales: Alharthi, Sitah, Popat, Amirali, Ziora, Zyta Maria, Moyle, Peter Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004702/
https://www.ncbi.nlm.nih.gov/pubmed/36903360
http://dx.doi.org/10.3390/molecules28052114