Ganoderic Acid A and Its Amide Derivatives as Potential Anti-Cancer Agents by Regulating the p53-MDM2 Pathway: Synthesis and Biological Evaluation

The mechanisms of action of natural products and the identification of their targets have long been a research hotspot. Ganoderic acid A (GAA) is the earliest and most abundant triterpenoids discovered in Ganoderma lucidum. The multi-therapeutic potential of GAA, in particular its anti-tumor activit...

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Detalles Bibliográficos
Autores principales: Jia, Yi, Li, Yan, Shang, Hai, Luo, Yun, Tian, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004777/
https://www.ncbi.nlm.nih.gov/pubmed/36903622
http://dx.doi.org/10.3390/molecules28052374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004777/
https://www.ncbi.nlm.nih.gov/pubmed/36903622
http://dx.doi.org/10.3390/molecules28052374

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