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Detection of Hepatitis C virus RNA using a novel hybridization chain reaction method that competitively dampens cascade amplification
The hybridization chain reaction (HCR) is widely used for biosensing. However, HCR does not provide the required sensitivity. In this study, we reported a method to improve the sensitivity of HCR by dampening the cascade amplification. First, we designed a biosensor based on HCR, and an initiator DN...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004832/ https://www.ncbi.nlm.nih.gov/pubmed/36897913 http://dx.doi.org/10.1371/journal.pone.0268917 |