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Detection of Hepatitis C virus RNA using a novel hybridization chain reaction method that competitively dampens cascade amplification

The hybridization chain reaction (HCR) is widely used for biosensing. However, HCR does not provide the required sensitivity. In this study, we reported a method to improve the sensitivity of HCR by dampening the cascade amplification. First, we designed a biosensor based on HCR, and an initiator DN...

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Detalles Bibliográficos
Autores principales: Zhang, Chen, Qu, Qingrong, Yao, Yuming, Fan, Xiaobo, Wu, Guoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004832/
https://www.ncbi.nlm.nih.gov/pubmed/36897913
http://dx.doi.org/10.1371/journal.pone.0268917