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Bruton’s Tyrosine Kinase Inhibitors (BTKIs): Review of Preclinical Studies and Evaluation of Clinical Trials

In the last few decades, there has been a growing interest in Bruton’s tyrosine kinase (BTK) and the compounds that target it. BTK is a downstream mediator of the B-cell receptor (BCR) signaling pathway and affects B-cell proliferation and differentiation. Evidence demonstrating the expression of BT...

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Detalles Bibliográficos
Autores principales: Rozkiewicz, Dariusz, Hermanowicz, Justyna Magdalena, Kwiatkowska, Iwona, Krupa, Anna, Pawlak, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005125/
https://www.ncbi.nlm.nih.gov/pubmed/36903645
http://dx.doi.org/10.3390/molecules28052400