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Brain Uptake of Folate Forms in the Presence of Folate Receptor Alpha Antibodies in Young Rats: Folate and Antibody Distribution

In a rat model, following exposure to rat folate receptor alpha antibodies (FRαAb) during gestation, FRαAb accumulates in the placenta and the fetus and blocks folate transport to the fetal brain and produces behavioral deficits in the offspring. These deficits could be prevented with folinic acid....

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Detalles Bibliográficos
Autores principales: Bobrowski-Khoury, Natasha, Sequeira, Jeffrey M., Quadros, Edward V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005127/
https://www.ncbi.nlm.nih.gov/pubmed/36904166
http://dx.doi.org/10.3390/nu15051167