Novel Xanomeline-Containing Bitopic Ligands of Muscarinic Acetylcholine Receptors: Design, Synthesis and FRET Investigation

In the last few years, fluorescence resonance energy transfer (FRET) receptor sensors have contributed to the understanding of GPCR ligand binding and functional activation. FRET sensors based on muscarinic acetylcholine receptors (mAChRs) have been employed to study dual-steric ligands, allowing fo...

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Detalles Bibliográficos
Autores principales: Matera, Carlo, Kauk, Michael, Cirillo, Davide, Maspero, Marco, Papotto, Claudio, Volpato, Daniela, Holzgrabe, Ulrike, De Amici, Marco, Hoffmann, Carsten, Dallanoce, Clelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005175/
https://www.ncbi.nlm.nih.gov/pubmed/36903650
http://dx.doi.org/10.3390/molecules28052407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005175/
https://www.ncbi.nlm.nih.gov/pubmed/36903650
http://dx.doi.org/10.3390/molecules28052407

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