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Design of a minimal di-nickel hydrogenase peptide

Ancestral metabolic processes involve the reversible oxidation of molecular hydrogen by hydrogenase. Extant hydrogenase enzymes are complex, comprising hundreds of amino acids and multiple cofactors. We designed a 13–amino acid nickel-binding peptide capable of robustly producing molecular hydrogen...

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Detalles Bibliográficos
Autores principales: Timm, Jennifer, Pike, Douglas H., Mancini, Joshua A., Tyryshkin, Alexei M., Poudel, Saroj, Siess, Jan A., Molinaro, Paul M., McCann, James J., Waldie, Kate M., Koder, Ronald L., Falkowski, Paul G., Nanda, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005181/
https://www.ncbi.nlm.nih.gov/pubmed/36897954
http://dx.doi.org/10.1126/sciadv.abq1990