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Sex-Specific Response of the Brain Free Oxylipin Profile to Soluble Epoxide Hydrolase Inhibition

Oxylipins are the oxidation products of polyunsaturated fatty acids and have been implicated in neurodegenerative disorders, including dementia. Soluble epoxide hydrolase (sEH) converts epoxy-fatty acids to their corresponding diols, is found in the brain, and its inhibition is a treatment target fo...

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Detalles Bibliográficos
Autores principales: Norman, Jennifer E., Nuthikattu, Saivageethi, Milenkovic, Dragan, Rutledge, John C., Villablanca, Amparo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005333/
https://www.ncbi.nlm.nih.gov/pubmed/36904213
http://dx.doi.org/10.3390/nu15051214