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Biomimetic Nanozymes Suppressed Ferroptosis to Ameliorate Doxorubicin-Induced Cardiotoxicity via Synergetic Effect of Antioxidant Stress and GPX4 Restoration

Mitochondria-dependent ferroptosis plays an important role in the pathogenesis of doxorubicin (DOX)-induced cardiotoxicity (DIC), which remains a clinical challenge due to the lack of effective interventions. Cerium oxide (CeO(2)), a representative nanozyme, has attracted much attention because of i...

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Detalles Bibliográficos
Autores principales: Zhang, Yunpeng, Liu, Shuang, Peng, Jing, Cheng, Shifeng, Zhang, Qingling, Zhang, Nan, Zhou, Zandong, Zhang, Yue, Zhao, Yang, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005374/
https://www.ncbi.nlm.nih.gov/pubmed/36904089
http://dx.doi.org/10.3390/nu15051090