Isolation and Characterization of an Unknown Process-Related Impurity in Furosemide and Validation of a New HPLC Method

Furosemide is a widely used loop diuretic in the treatment of congestive heart failure and edema. During the preparation of furosemide, a new process-related impurity G in the levels ranging from 0.08% to 0.13% was detected in pilot batches by a new high performance liquid chromatography (HPLC) meth...

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Detalles Bibliográficos
Autores principales: Xu, Ao, Xue, Yunlin, Zeng, Yuyu, Li, Jing, Zhou, Huiling, Wang, Zhen, Chen, Yin, Chen, Hui, Jin, Jian, Zhuang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005432/
https://www.ncbi.nlm.nih.gov/pubmed/36903659
http://dx.doi.org/10.3390/molecules28052415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005432/
https://www.ncbi.nlm.nih.gov/pubmed/36903659
http://dx.doi.org/10.3390/molecules28052415

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