In Silico Exploration of Microtubule Agent Griseofulvin and Its Derivatives Interactions with Different Human β-Tubulin Isotypes

Tubulin isotypes are known to regulate microtubule stability and dynamics, as well as to play a role in the development of resistance to microtubule-targeted cancer drugs. Griseofulvin is known to disrupt cell microtubule dynamics and cause cell death in cancer cells through binding to tubulin prote...

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Detalles Bibliográficos
Autores principales: Aris, Parisa, Mohamadzadeh, Masoud, Kruglikov, Alibek, Askari Rad, Mahbubeh, Xia, Xuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005519/
https://www.ncbi.nlm.nih.gov/pubmed/36903629
http://dx.doi.org/10.3390/molecules28052384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005519/
https://www.ncbi.nlm.nih.gov/pubmed/36903629
http://dx.doi.org/10.3390/molecules28052384

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