Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates

Differentiation of B cells into antibody-secreting cells (ASCs) is a key process to generate protective humoral immunity. A detailed understanding of the cues controlling ASC differentiation is important to devise strategies to modulate antibody formation. Here, we dissected differentiation trajecto...

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Detalles Bibliográficos
Autores principales: Verstegen, Niels JM, Pollastro, Sabrina, Unger, Peter-Paul A, Marsman, Casper, Elias, George, Jorritsma, Tineke, Streutker, Marij, Bassler, Kevin, Haendler, Kristian, Rispens, Theo, Schultze, Joachim L, ten Brinke, Anja, Beyer, Marc, van Ham, S Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005767/
https://www.ncbi.nlm.nih.gov/pubmed/36861964
http://dx.doi.org/10.7554/eLife.83578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005767/
https://www.ncbi.nlm.nih.gov/pubmed/36861964
http://dx.doi.org/10.7554/eLife.83578

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