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Cigarette smoke preferentially induces full length ACE2 expression in differentiated primary human airway cultures but does not alter the efficiency of cellular SARS-CoV-2 infection

Cigarette smoking has many serious negative health consequences. The relationship between smoking and SARS-CoV-2 infection is controversial, specifically whether smokers are at increased risk of infection. We investigated the impact of cigarette smoke on ACE2 isoform expression and SARS-CoV-2 infect...

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Detalles Bibliográficos
Autores principales: Porter, Linsey M., Guo, Wenrui, Crozier, Thomas WM., Greenwood, Edward JD., Ortmann, Brian, Kottmann, Daniel, Nathan, James A., Mahadeva, Ravindra, Lehner, Paul J., McCaughan, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005841/
https://www.ncbi.nlm.nih.gov/pubmed/36938474
http://dx.doi.org/10.1016/j.heliyon.2023.e14383