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Brain gene therapy with Trojan horse lipid nanoparticles

The COVID-19 mRNA vaccine was developed by the scalable manufacture of lipid nanoparticles (LNPs) that encapsulate mRNA within the lipid. There are many potential applications for this large nucleic acid delivery technology, including the delivery of plasmid DNA for gene therapy. However, gene thera...

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Detalles Bibliográficos
Autor principal: Pardridge, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005896/
https://www.ncbi.nlm.nih.gov/pubmed/36907687
http://dx.doi.org/10.1016/j.molmed.2023.02.004