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SARS-CoV-2 Mutations Lead to a Decrease in the Number of Tissue-Specific MicroRNA-Binding Regions in the Lung

RNA interference in vertebrates acts as an antiviral mechanism only in undifferentiated embryonic stem cells and is mediated by microRNAs. In somatic cells, host microRNAs also bind to the genomes of RNA viruses, regulating their translation and replication. It has been shown that viral (+)RNA can e...

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Detalles Bibliográficos
Autores principales: Zhiyanov, A. P., Shkurnikov, M. Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005917/
https://www.ncbi.nlm.nih.gov/pubmed/36899205
http://dx.doi.org/10.1007/s10517-023-05742-0