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N-Acetylcysteine normalizes brain oxidative stress and neuroinflammation observed after protracted ethanol abstinence: a preclinical study in long-term ethanol-experienced male rats

RATIONALE: Using a preclinical model based on the Alcohol Deprivation Effect (ADE), we have reported that N-Acetylcysteine (NAC) can prevent the relapse-like drinking behaviour in long-term ethanol-experienced male rats. OBJECTIVES: To investigate if chronic ethanol intake and protracted abstinence...

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Detalles Bibliográficos
Autores principales: Fernández-Rodríguez, Sandra, Cano-Cebrián, María José, Esposito-Zapero, Claudia, Pérez, Salvador, Guerri, Consuelo, Zornoza, Teodoro, Polache, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006045/
https://www.ncbi.nlm.nih.gov/pubmed/36708386
http://dx.doi.org/10.1007/s00213-023-06311-z