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Alternatively spliced exon regulates context-dependent MEF2D higher-order assembly during myogenesis

During muscle cell differentiation, the alternatively spliced, acidic β-domain potentiates transcription of Myocyte-specific Enhancer Factor 2 (Mef2D). Sequence analysis by the FuzDrop method indicates that the β-domain can serve as an interaction element for Mef2D higher-order assembly. In accord,...

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Detalles Bibliográficos
Autores principales: Gönczi, Mónika, Teixeira, João M. C., Barrera-Vilarmau, Susana, Mediani, Laura, Antoniani, Francesco, Nagy, Tamás Milán, Fehér, Krisztina, Ráduly, Zsolt, Ambrus, Viktor, Tőzsér, József, Barta, Endre, Kövér, Katalin E., Csernoch, László, Carra, Serena, Fuxreiter, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006080/
https://www.ncbi.nlm.nih.gov/pubmed/36898987
http://dx.doi.org/10.1038/s41467-023-37017-7