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Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1

TANK-binding kinase 1 (TBK1) is an essential protein kinase for activation of interferon regulatory factor 3 (IRF3) and induction of the type I interferons (IFN-I). Although the biochemical regulation of TBK1 activation has been studied, little is known about how enterovirus 71 (EV71) employs the de...

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Detalles Bibliográficos
Autores principales: Zang, Lichao, Gu, Jin, Yang, Xinyu, Yuan, Yukang, Guo, Hui, Zhou, Wei, Ma, Jinhong, Chen, Yan, Wu, Yumin, Zheng, Hui, Shi, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006192/
https://www.ncbi.nlm.nih.gov/pubmed/36334706
http://dx.doi.org/10.1016/j.virs.2022.11.001