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PTBP1 drives c-Myc-dependent gastric cancer progression and stemness

BACKGROUND: Gastric cancer (GC) tumorigenesis and treatment failure are caused by cancer stem cells. Polypyrimidine tract binding protein 1 (PTBP1) was shown to be involved in the development of embryonic stem cells and is now being considered as a therapeutic target for tumour progression and stem-...

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Detalles Bibliográficos
Autores principales: Ni, Tengyang, Chu, Zewen, Tao, Li, Zhao, Yang, Zhu, Miao, Luo, Yuanyuan, Sunagawa, Masataka, Wang, Haibo, Liu, Yanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006230/
https://www.ncbi.nlm.nih.gov/pubmed/36635500
http://dx.doi.org/10.1038/s41416-022-02118-5