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Identifying polymorphic cis-regulatory variants as risk markers for lung carcinogenesis and chemotherapy responses in tobacco smokers from eastern India

Aberrant expression of xenobiotic metabolism and DNA repair genes is critical to lung cancer pathogenesis. This study aims to identify the cis-regulatory variants of the genes modulating lung cancer risk among tobacco smokers and altering their chemotherapy responses. From a list of 2984 SNVs, prior...

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Detalles Bibliográficos
Autores principales: Sengupta, Debmalya, Mukhopadhyay, Pramiti, Banerjee, Souradeep, Ganguly, Kausik, Mascharak, Prateek, Mukherjee, Noyonika, Mitra, Sangeeta, Bhattacharjee, Samsiddhi, Mitra, Ritabrata, Sarkar, Abhijit, Chaudhuri, Tamohan, Bhattacharjee, Gautam, Nath, Somsubhra, Roychoudhury, Susanta, Sengupta, Mainak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006236/
https://www.ncbi.nlm.nih.gov/pubmed/36899086
http://dx.doi.org/10.1038/s41598-023-30962-9