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Imaging the Alternatively Spliced D Domain of Tenascin C in a Preclinical Model of Inflammatory Bowel Disease

PURPOSE: To image colon-expressed alternatively spliced D domain of tenascin C in preclinical colitis models using near infrared (NIR)-labeled targeted molecular imaging agents. Procedures. A human IgG1 with nanomolar binding affinity specific to the alternatively spliced D domain of tenascin C was...

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Detalles Bibliográficos
Autores principales: Zhang, Liang, Wang, Yuzhen, Homan, Kristoff T., Gaudette, Stephanie M., McCluskey, Andrew J., Chan, Ying, Murphy, Joanne, Abdalla, Mary, Nelson, Christine M., Sun, Victor Z., Erickson, Jamie E., Knight, Heather L., Clabbers, Anca, Sterman, Annette J. Schwartz, Mitra, Soumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006278/
https://www.ncbi.nlm.nih.gov/pubmed/35906512
http://dx.doi.org/10.1007/s11307-022-01758-6