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ApoM binds endotoxin contributing to neutralization and clearance by High Density Lipoprotein

BACKGROUND: HDL possesses anti-inflammatory properties, however, the exact mechanism is not fully understood. Endotoxin is a potent inducers of TLR4 signaling, leading to inflammatory mediators’ release. It has been estimated that TLR4 recognizes about 5% of circulating lipopolysaccharide whereas 95...

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Detalles Bibliográficos
Autores principales: Mousa, Hanaa, Thanassoulas, Angelos, Zughaier, Susu M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006442/
https://www.ncbi.nlm.nih.gov/pubmed/36915826
http://dx.doi.org/10.1016/j.bbrep.2023.101445