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Modeling incomplete penetrance in arrhythmogenic cardiomyopathy by human induced pluripotent stem cell derived cardiomyocytes

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are commonly used to model arrhythmogenic cardiomyopathy (ACM), a heritable cardiac disease characterized by severe ventricular arrhythmias, fibrofatty myocardial replacement and progressive ventricular dysfunction. Although ACM...

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Detalles Bibliográficos
Autores principales: De Bortoli, Marzia, Meraviglia, Viviana, Mackova, Katarina, Frommelt, Laura S., König, Eva, Rainer, Johannes, Volani, Chiara, Benzoni, Patrizia, Schlittler, Maja, Cattelan, Giada, Motta, Benedetta M., Volpato, Claudia, Rauhe, Werner, Barbuti, Andrea, Zacchigna, Serena, Pramstaller, Peter P., Rossini, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006475/
https://www.ncbi.nlm.nih.gov/pubmed/36915380
http://dx.doi.org/10.1016/j.csbj.2023.02.029