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Human corneal stromal stem cells express anti-fibrotic microRNA-29a and 381-5p – A robust cell selection tool for stem cell therapy of corneal scarring

INTRODUCTION: Corneal blindness due to scarring is treated with corneal transplantation. However, a global problem is the donor material shortage. Preclinical and clinical studies have shown that cell-based therapy using corneal stromal stem cells (CSSCs) suppresses corneal scarring, potentially med...

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Detalles Bibliográficos
Autores principales: Yam, Gary Hin-Fai, Yang, Tianbing, Geary, Moira L, Santra, Mithun, Funderburgh, Martha, Rubin, Elizabeth, Du, Yiqin, Sahel, Jose A, Jhanji, Vishal, Funderburgh, James L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006527/
https://www.ncbi.nlm.nih.gov/pubmed/35623612
http://dx.doi.org/10.1016/j.jare.2022.05.008