Turning chiral peptides into a racemic supraparticle to induce the self-degradation of MDM2

INTRODUCTION: Chirality is immanent in nature, and chiral molecules can achieve their pharmacological action through chiral matching with biomolecules and molecular conformation recognition. OBJECTIVES: Clinical translation of chiral therapeutics, particularly chiral peptide molecules, has been hamp...

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Detalles Bibliográficos
Autores principales: Yang, Wenguang, Liu, Wenjia, Li, Xiang, Yan, Jin, He, Wangxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006529/
https://www.ncbi.nlm.nih.gov/pubmed/35667548
http://dx.doi.org/10.1016/j.jare.2022.05.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006529/
https://www.ncbi.nlm.nih.gov/pubmed/35667548
http://dx.doi.org/10.1016/j.jare.2022.05.009

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