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Turning chiral peptides into a racemic supraparticle to induce the self-degradation of MDM2
INTRODUCTION: Chirality is immanent in nature, and chiral molecules can achieve their pharmacological action through chiral matching with biomolecules and molecular conformation recognition. OBJECTIVES: Clinical translation of chiral therapeutics, particularly chiral peptide molecules, has been hamp...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006529/ https://www.ncbi.nlm.nih.gov/pubmed/35667548 http://dx.doi.org/10.1016/j.jare.2022.05.009 |