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Mass spectrometric investigations of the action of hypochlorous acid on monomeric and oligomeric components of glycosaminoglycans

Hypochlorous acid (HOCl) is a strong non-radical oxidant, which is generated during inflammatory processes under the catalysis of the enzyme myeloperoxidase (MPO). HOCl reacts particularly with sulfhydryl and amino acid residues but affects also many other biomolecules. For instance, the glycosamino...

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Detalles Bibliográficos
Autores principales: Leopold, Jenny, Prabutzki, Patricia, Nimptsch, Ariane, Schiller, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006533/
https://www.ncbi.nlm.nih.gov/pubmed/36915825
http://dx.doi.org/10.1016/j.bbrep.2023.101448