Translational characterization of the temporal dynamics of metabolic dysfunctions in liver, adipose tissue and the gut during diet-induced NASH development in Ldlr−/−.Leiden mice

BACKGROUND: NAFLD progression, from steatosis to inflammation and fibrosis, results from an interplay of intra- and extrahepatic mechanisms. Disease drivers likely include signals from white adipose tissue (WAT) and gut. However, the temporal dynamics of disease development remain poorly understood....

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Detalles Bibliográficos
Autores principales: Gart, Eveline, van Duyvenvoorde, Wim, Snabel, Jessica M., de Ruiter, Christa, Attema, Joline, Caspers, Martien P.M., Lek, Serene, van Heuven, Bertie Joan, Speksnijder, Arjen G.C.L., Giera, Martin, Menke, Aswin, Salic, Kanita, Bence, Kendra K., Tesz, Gregory J., Keijer, Jaap, Kleemann, Robert, Morrison, Martine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006542/
https://www.ncbi.nlm.nih.gov/pubmed/36915476
http://dx.doi.org/10.1016/j.heliyon.2023.e13985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006542/
https://www.ncbi.nlm.nih.gov/pubmed/36915476
http://dx.doi.org/10.1016/j.heliyon.2023.e13985

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