Phenotype-specific estimation of metabolic fluxes using gene expression data

A cell’s genome influences its metabolism via the expression of enzyme-related genes, but transcriptome and fluxome are not perfectly correlated as post-transcriptional mechanisms also regulate reaction’s kinetics. Here, we addressed the question: given a transcriptome, how unobserved mechanisms of...

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Detalles Bibliográficos
Autores principales: González-Arrué, Nicolás, Inostroza, Isidora, Conejeros, Raúl, Rivas-Astroza, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006673/
https://www.ncbi.nlm.nih.gov/pubmed/36915687
http://dx.doi.org/10.1016/j.isci.2023.106201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006673/
https://www.ncbi.nlm.nih.gov/pubmed/36915687
http://dx.doi.org/10.1016/j.isci.2023.106201

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