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Phenotype-specific estimation of metabolic fluxes using gene expression data
A cell’s genome influences its metabolism via the expression of enzyme-related genes, but transcriptome and fluxome are not perfectly correlated as post-transcriptional mechanisms also regulate reaction’s kinetics. Here, we addressed the question: given a transcriptome, how unobserved mechanisms of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006673/ https://www.ncbi.nlm.nih.gov/pubmed/36915687 http://dx.doi.org/10.1016/j.isci.2023.106201 |