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Single-cell RNA sequencing identifies hippocampal microglial dysregulation in diet-induced obesity
Obesity is a growing global concern in adults and youth with a parallel rise in associated complications, including cognitive impairment. Obesity induces brain inflammation and activates microglia, which contribute to cognitive impairment by aberrantly phagocytosing synaptic spines. Local and system...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006681/ https://www.ncbi.nlm.nih.gov/pubmed/36915697 http://dx.doi.org/10.1016/j.isci.2023.106164 |