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Single-cell RNA sequencing identifies hippocampal microglial dysregulation in diet-induced obesity

Obesity is a growing global concern in adults and youth with a parallel rise in associated complications, including cognitive impairment. Obesity induces brain inflammation and activates microglia, which contribute to cognitive impairment by aberrantly phagocytosing synaptic spines. Local and system...

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Detalles Bibliográficos
Autores principales:	Henn, Rosemary E., Guo, Kai, Elzinga, Sarah E., Noureldein, Mohamed H., Mendelson, Faye E., Hayes, John M., Rigan, Diana M., Savelieff, Masha G., Hur, Junguk, Feldman, Eva L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006681/ https://www.ncbi.nlm.nih.gov/pubmed/36915697 http://dx.doi.org/10.1016/j.isci.2023.106164

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