Pharmacological inhibition of the SKP2/p300 signaling axis restricts castration-resistant prostate cancer

SKP2, an F-box protein of the SCF type of the E3 ubiquitin ligase complex, plays an important function in driving tumorigenesis through the destruction of numerous tumor-suppressive proteins. Besides its critical role in cell cycle regulation, proto-oncogenic functions of SKP2 have also been shown i...

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Detalles Bibliográficos
Autores principales: Rezaeian, Abdol-Hossein, Phan, Liem Minh, Zhou, Xiaobo, Wei, Wenyi, Inuzuka, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006859/
https://www.ncbi.nlm.nih.gov/pubmed/36871351
http://dx.doi.org/10.1016/j.neo.2023.100890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006859/
https://www.ncbi.nlm.nih.gov/pubmed/36871351
http://dx.doi.org/10.1016/j.neo.2023.100890

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