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Pharmacological inhibition of the SKP2/p300 signaling axis restricts castration-resistant prostate cancer
SKP2, an F-box protein of the SCF type of the E3 ubiquitin ligase complex, plays an important function in driving tumorigenesis through the destruction of numerous tumor-suppressive proteins. Besides its critical role in cell cycle regulation, proto-oncogenic functions of SKP2 have also been shown i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Neoplasia Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006859/ https://www.ncbi.nlm.nih.gov/pubmed/36871351 http://dx.doi.org/10.1016/j.neo.2023.100890 |