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Combination of Cellulose Derivatives and Chitosan-Based Polymers to Investigate the Effect of Permeation Enhancers Added to In Situ Nasal Gels for the Controlled Release of Loratadine and Chlorpheniramine

The purpose of the study is to develop and assess mucoadhesive in situ nasal gel formulations of loratadine and chlorpheniramine maleate to advance the bioavailability of the drug as compared to its conventional dosage forms. The influence of various permeation enhancers, such as EDTA (0.2% w/v), so...

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Detalles Bibliográficos
Autores principales: Viswanadhan Vasantha, Prasanth, Sherafudeen, Sheri Peedikayil, Rahamathulla, Mohamed, Mathew, Sam Thomarayil, Murali, Sandhya, Alshehri, Sultan, Shakeel, Faiyaz, Alam, Prawez, Sirhan, Ala Yahya, Narayana Iyer, Bhageerathy Anantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10006938/
https://www.ncbi.nlm.nih.gov/pubmed/36904447
http://dx.doi.org/10.3390/polym15051206