Specificity protein 1-mediated ACSL4 transcription promoted the osteoarthritis progression through suppressing the ferroptosis of chondrocytes

BACKGROUND: Chondrocytes are the main cell damage type involved in the occurrence and development of osteoarthritis (OA). Ferroptosis has been confirmed to be related to many degenerative diseases. This research aimed to explore the role of Sp1 and ACSL4 in ferroptosis in the IL-1β-treated human cho...

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Detalles Bibliográficos
Autores principales: He, Wen, Lin, Xuchao, Chen, Kangyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007726/
https://www.ncbi.nlm.nih.gov/pubmed/36899378
http://dx.doi.org/10.1186/s13018-023-03673-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007726/
https://www.ncbi.nlm.nih.gov/pubmed/36899378
http://dx.doi.org/10.1186/s13018-023-03673-0

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