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Isorhynchophylline inhibits inflammatory responses in endothelial cells and macrophages through the NF-κB/NLRP3 signaling pathway

BACKGROUND: Atherosclerosis is a chronic inflammatory disease of arterial wall, which is closely related to inflammatory reaction. In this study, the anti-inflammatory effect of isorhynchophylline was studied by NF- κB / NLRP3 pathway. METHODS: (1) ApoE(−/−) mice were fed with high-fat diet to estab...

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Detalles Bibliográficos
Autores principales: Wang, Li-Hua, Gu, Zheng-Wei, Li, Jie, Yang, Wen-Qing, Li, Yun-Lun, Qi, Dong-Mei, Wang, Dan-Yang, Jiang, Hai-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007741/
https://www.ncbi.nlm.nih.gov/pubmed/36906555
http://dx.doi.org/10.1186/s12906-023-03902-3