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Anemonin reduces hydrogen peroxide-induced oxidative stress, inflammation and extracellular matrix degradation in nucleus pulposus cells by regulating NOX4/NF-κB signaling pathway

BACKGROUND: Excessive oxidative stress plays a critical role in the progression of various diseases, including intervertebral disk degeneration (IVDD). Recent studies have found that anemonin (ANE) possesses antioxidant and anti-inflammatory effects. However, the role of ANE in IVDD is still unclear...

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Detalles Bibliográficos
Autores principales: Ma, Zhijia, Yu, Pengfei, Li, Xiaochun, Dai, Feng, Jiang, Hong, Liu, Jintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10007850/
https://www.ncbi.nlm.nih.gov/pubmed/36899420
http://dx.doi.org/10.1186/s13018-023-03679-8